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Despite the widespread use of CPZ, the mechanism by which it induces demyelination and allows spontaneous remyelination without damaging to other types of neural cells in the brain, is still unclear

223 The first reaction of LA metabolism is the hydration of the 9,10-alkene catalyzed by CLA-HY, which exhibits both hydratase and dehydratase activities and converts LA into 12( Z )-10( S )-HOME

[DOI] [PMC free article] [PubMed] [Google Scholar] 118.Chen T., Turner B.J., Beart P.M., Sheehan-Hennessy L., Elekwachi C., Muyderman H

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