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Chapter 30

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The results of our study demonstrated a marked reduction of HM induced OS with EECGL supplementation, suggesting the role of EECGL in preventing HM induced systemic anomalies either by directly acting as a ROS scavenger or by indirectly modifying the cell signalling system which altered the redox-equilibrium

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tuberculosis invasion, macrophages deploy a repertoire of defense strategies, including phagosome-lysosome fusion to degrade pathogens, recruitment of hydrolytic lysosomal enzymes, production of reactive oxygen species (ROS) and reactive nitrogen species (RNS), antigen presentation, upregulation and mobilization of major histocompatibility complex class II (MHC class II) molecules, autophagy, and induction of apoptosis (36)

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Ambrosino P, Bachetti T, DAnna SE, Galloway B, Bianco A, DAgnano V, et al

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