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Because a large number of comparisons were performed on the relative abundance data, main effect results from these analyses also underwent a BenjaminiHochberg false discovery rate (FDR) correction for multiple comparisons, and instances where a result was significant after this correction have been duly noted

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ADVANCED DIAGNOSTICS: For high clinical suspicion with low-normal B12 levels, measure Methylmalonic Acid (MMA) and Homocysteine for early, accurate detection

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adults older than 50 years are estimated to have a serum vitamin B 12 level less than 200 pg per mL

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