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Voxel-based lesionsymptom mapping studies have shown that damage to key subcortical-frontal connections such as the anterior thalamic radiation and forceps minor by both WMH and lacunes is associated with low processing speed and executive dysfunctions

Hugenholtz P

It typically affects men as they get older, but it can also develop in men that are in their twenties and thirties

Although isoform X1 is absent in certain higher organisms, such as mice, elephants, dogs and chickens, it is highly conserved across many other species ( via the inhibition of NOTCH1 signaling

A meta-analysis of cohort studies involving 355,230 participants found that high dietary cholesterol intake was associated with a 15% increased risk of T2DM (RR: 1.15