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Description
B12 is water-soluble, with excess typically excreted in urine, and anxiety is not listed as a recognised adverse effect in MHRA product information

Clinical pharmacogenetics implementation consortium guideline (CPIC) for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants: 2016 update

This suggestion contrasted starkly with the prevalent Enlightenment-era attitude that scientific observation can only be objectively valid when undertaken by a well-educated, informed scientist

Benefits accrue over weeks to months rather than immediate effects

Chen Z, Hu T, Zhu S, Mukaisho K, El-Rifai W, Peng DF
