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These products are formed through the interaction of ROS with lipids, leading to cell membrane damage, protein modification, and DNA injury, thereby accelerating disease progression [129]

Fibroids also tend to cause heavy bleeding, often resulting in patients developing anemia and the associated symptoms due to low levels of iron present in their blood

The progression of NIHL involves an intricate interplay of biological processes, among which oxidative stress, inflammation and immune responses play pivotal roles (Fig

doi: 10.1016/j.toxicon.2010.03.010 66 SenthilkumaranSDavidSSMenezesRGThirumalaikolundusubramanianP

ABCB1 , another drug resistanceinducing gene, was knocked down using CRISPR/Cas9 in one study, resulting in enhanced drug sensitivity in adriamycin-resistant ovarian cancer cell lines (29)