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Conjugates formed between glutathione and toxic metabolites are further metabolised into cysteinyl-s-conjugates, which have long half-lives in circulation

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Please put your questions related to Episodes 1 & 2 in the comments section below so I can address them in Episode 3 "Office Hours"

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Gica N, Panaitescu AM, Iancu G, Botezatu R, Peltecu G, Gica C

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Inositol phosphate kinases: expanding the biological significance of the universal core of the protein kinase fold

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Methyl-THF cannot be converted back to methylene-THF because this reaction is not reversible (Figure 3)

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