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We excluded studies that looked at lower extremity wounds and neuropathy rather than DFUs specifically (as this review is specific to DFUs)

The intervention by the repair systems consists of repairing oxidatively damaged nucleic acids by specific enzymes, removing oxidized proteins by the proteolytic systems, and repairing oxidized lipids by phospholipases, peroxidases, or acryl transferases [8,39,40]

The lack of formation of NADPH can lead to a reduction in red blood cells' ability to withstand oxidative stress with the administration of certain drugs or during infections, thus resulting in hemolytic anemia

To view a copy of this licence, visit About this article Cite this article Chen, S., Yoon, JS., Park, EJ

N., Fabro A., Miranda C
