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Since skn-1 showed no changes in expression in response to the glucose-fed bacterial diet, we further tested one of its target genes, gcs-1 , often used as a surrogate for skn-1 41

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The reason for choosing the latter is that it is one of the signalling pathways mediating the interactions between stromal and cancer cells and plays a major role in promoting cancer progression

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For the benefit of providing a substrate to these enzymes, it is generally thought that dietary protein is required for an effective detoxification protocol

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In 2025, the FDA approved elamipretide, manufactured by Stealth BioTherapeutics, to improve muscle strength in patients with Barth syndrome [4]

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