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Patients at risk of RA have immune abnormalities, gut microbiota may affect gut immunity by regulating T cell-mediated mucosal immunity (Xu et al., 2020).The gut microbiota interacts with T cells through antigen-specific recognition or signals through toll like receptors (TLRs) and nod like receptors (NLRs)

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However, the mechanisms that allow cells to choose among different cell death modalities are still enigmatic

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