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Description
NRF2 is regulated through two principal mechanisms: post-translational modifications (PTMs) and epigenetic alterations

These transcriptomic changes are consistent with the pronounced intracellular ROS accumulation observed experimentally, supporting a redox imbalancedriven cellular stress response
ii) Heavy metal and combined stress response

In the early stages, varying degrees of fatigue, weight gain, and cognitive decline may be observed

The immune system doesnt age in isolation