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The TGR inhibitor demonstrating greatest efficacy in treating infected mice, 2 , was also studied after oral administration: 2 (200 mg/kg p.o.) gave plasma concentrations of 0.71, 0.77, and 0.40 M at 30, 60, and 120 min, respectively (Supplementary Table 19)

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Another is the fact that many organs consist of multiple cell types which can possess different glutathione levels and forms

Recent studies further indicate that salinity tolerance arises from dynamic, tissue-specific responses integrating signaling pathways, ion transport systems, and growth regulation across multiple organizational levels
