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Conversely, cancer cells were less sensitive to inhibitors of cystine uptake (for example, erastin) and the thioredoxin pathway (for example, auranofin, aurothioglucose and PX-12) (Fig

Eur J Neurosci 27:16731685 Braissant O, Henry H, Villard AM, Zurich MG, Loup M, Eilers B, Parlascino G, Matter E, Boulat O, Honegger P, Bachmann C (2002) Ammonium induced impairment of axonal growth is prevented through glial creatine

In parallel, the review examines the current status of clinical translation, summarizing key challenges such as limited bioavailability, formulation barriers, and patientspecific variability, while highlighting emerging opportunities including nanodelivery platforms, combination therapeutic strategies, and precision medicineoriented applications

Heterotopic syngeneic transplantation Nine- to 10 week-old (W9-10) female mice of both genotypes ( Igf1r fl/fl and UBC-Cre-ERT2

Oncotarget 8(21):3412834140
