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Indeed, TJs allow the paracellular transport of some medium-sized hydrophilic molecules, ions, or positively charged molecules but prevent the transport of proteins, such as antigenic macromolecules, lipids, and microbial-derived peptides (168)

However, no antidepressant should be a priori avoided in the case of concomitant administration with PIs

The increase of AIDS-like pathologies in ageing rats implies a progressive burden of HIV related protein expression and consequent tissue injury over time

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