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In addition, they can also induce Tregs expansion by secreting IL-10 and TGF-, thereby indirectly inhibiting T cell function [124]

However, concentrations of TGF- in BALF increase also in other sclerosing diseases, such as stage IV sarcoidosis and systemic sclerosis [87]

In 1992, the General Accounting Office (GAO)the historical predecessor to the Government Accountability Officereleased the report Womens Health: FDA Needs to Ensure More Study of Gender Differences in Prescription Drug Testing, ushering a new era of focus on the issue of diversity in clinical trials
