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The cells were grown at 37 C in a humidified incubator containing 5% CO 2

The fact that these macrophages can restore motility even in the late stages of the disease model indicates that immune cells could be effective drug carriers across the BBB[188] (Fig

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Mayell, M

Lineage-tracing studies performed in vivo in transgenic mice with conditional Cre/Lox alleles have shown that Notch1 / and dominant negative Trp53 mutant ( Trp53 R245W ) mutant clones have a competitive advantage in normal mouse esophagus 33,37 , correlating with the screen results