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As a result of these two mechanisms, AMPH increases the concentration of monoamines in the presynaptic neuron, leading to a reversal of the monoamine transporters to shuttle DA, NE, and 5-HT into the synaptic cleft [215]

Up to 55% of patients developed anti-drug antibodies [65], which were associated with systemic allergic reactions in approximately 5% of cases and injection-site hypersensitivity, including anaphylaxis, which necessitated early trial termination [66, 67]

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Ionescu L, Costea CF, Dnil R et al (2021) Thymus pathology in Myasthenia gravis with anti-acetylcholine receptor antibodies and concomitant Hashimotos thyroiditis

Lossoffunction mutations in the Arabidopsis cytosol-targeted DHAR2 form alone led to lower ascorbate/DHA ratios but did not affect total ascorbate accumulation (Yoshida et al