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The mainly vesicular intracellular localization of MRP1 in STB and pFECs was puzzling given the fact that these drug transporters are generally considered to be cell surface localized and to mediate drug resistance by lowering total intracellular drug concentrations

Initially, GHRPs were thought to mimic the growth hormone-releasing action of a newly discovered endogenous hypothalamic hormone

doi: 10.1007/s12011-009-8322-0

Because proteins function is dependent on their shape, denatured proteins are no longer functional

4 Median survival time of 29.3 months has been reported in cats with NC, with no difference between ANC and CNC