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The tight junction is organized by four types of transmembrane proteins, occludin, claudins, tricellulin and junctional adhesion molecules, which interact with the scaffold proteins such as ZO-1, ZO-2 and ZO-3 (62, 63)

Some examples include: Abaloparatide (Tymlos) and Teriparatide (Forteo) for osteoporosis Degarelix (Firmagon) for advanced prostate cancer Dulaglutide (Trulicity), exenatide (Byetta), liraglutide (Victoza), lixisenatide (Adlyxin), tirzepatide (Mounjaro), and semaglutide (Ozempic) for Type 2 diabetes Semaglutide (Wegovy) and tirzepatide (Zepbound) for weight loss Linaclotide (Linzess) for irritable bowel syndrome with constipation Ziconotide (Prialt) for severe chronic pain These medications are carefully designed to target specific receptors and biological pathways, allowing for precise treatment of certain conditions

Superoxide dismutase administration, a potential therapy against oxidative stress related diseases: Several routes of supplementation and proposal of an original mechanism of action

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