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The activation of NRF2, a key antioxidant regulator, through agents such as sulforaphane or bardoxolone methyl could further enhance cellular defenses against ferroptotic injury, offering a promising avenue for future IBD treatment (173, 176, 177)

[DOI] [PMC free article] [PubMed] [Google Scholar] 41.Jackson R.A., Nguyen M.L., Barrett A.N., Tan Y.Y., Choolani M.A., Chen E.S

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