pernicious anemia is treated with injections of vitamin b12 because deficiency can lead to anemia, a type megaloblastic caused by impaired absorption of vitamin B12. This condition affects red blood cell production and may cause fatigue, weakness Pernicious Anaemia: When Your Body
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however, the between-group comparison revealed a nonsignificant P -value ( P = 0.167)

Other research suggests that conditions like trigeminal neuralgia, which affects the facial nerves, can also improve with B12 supplementation

Most self-injection therapies take only a few minutes to prepare and administer
It is also sold as research-grade vials for off-label study

[PMC free article: PMC2702831] [PubMed: 19240062] 248