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Indeed, it is possible as suggested previously 7 that the over-expression of GSTs in homozygous mosquitoes could be protecting Plasmodium parasites against the damaging effects of reactive oxidative species (ROS)

The 2OH/4OH Ratio A low 2OH/4OH ratio, as seen in the slider below, indicates a preference for the more damaging 4-OH pathway

This immune activation may, in turn, affect the CNS, exacerbating fatigue and cognitive symptoms

Given the drop in its activity at elevated temperatures or under denaturation conditions, the group employed a crosslinking strategy that uses biselectrophiles that target pairs of Cys to enhance its stability
