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Chen KG, Lacayo NJ, Durn GE et al (2002) Preferential expression of a mutant allele of the amplified MDR 1 ( ABCB 1) gene in drug-resistant variants of a human sarcoma

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Mutant mice also show craniofacial and limb deformities, which were later attributed to an essential role for Flvcr in sensory neuron maintenance and T cell development (98)

In nonpathological conditions, GPx has been shown to be the enzyme degrading most of the H 2 O 2 by oxidizing reduced GSH into GSSG (Eq

1 Introduction Solid tumors are made up of tumor cells and the tumor microenvironment (TME) that includes various cells (immune cells and mesenchymal cells) and extracellular matrix (ECM) (1, 2)