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5-Amino-1MQ has been investigated in preclinical models as a selective inhibitor of NNMT, an enzyme that catalyses the methylation of nicotinamide and has been referenced in the literature in connection with cellular energy metabolism, NAD + -associated signalling pathways, and energy homeostasis

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10.1172/JCI10588 50 HongJ.-Y.ChungH.-J.LeeH.-J.ParkH

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