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Clin Endocrinol (2013) 79:40915

The BP fatty acids called linoleic and linolenic combine with histamine H1 receptor while flavonoids decrease the production of nitric oxide and both act synergistically by diminishing the inflammatory responses (120)

[DOI] [PubMed] [Google Scholar] 96.Mazaleuskaya L.L., Theken K.N., Gong L., Thorn C.F., FitzGerald G.A., Altman R.B., Klein T.E
The mast cell in interstitial cystitis: role in pathophysiology and pathogenesis

In some cases, they may recommend a B-vitamin injection
