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29 Objectives Our present study revealed that the overexpression of GSTP1 could promote the proliferation, invasion and metastasis of CRC cells by upregulating STAT3, and that FBX8 could regulate this function
Werle et al., 2009)

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Future studies should integrate artificial intelligence and organoid technology, including human pluripotent stem cell (hPSC)-derived kidney organoids to simulate DN pathology (Xu et al., 2025), thereby accelerating TCM target screening and efficacy evaluation
