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nAChRs are ligand-gated ion channels composed of five transmembrane subunits, with the 4 2 receptor subtype being the most common in the brain, playing a crucial role in the behavioral effects of nicotine

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SIRT1, a target in the inflammatory response of articular chondrocytes is activated by curcumin, which protects chondrocytes by inhibiting MMP-13 and NF-B expression

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TLR2 and TLR4 are overexpressed in the blood and brain tissues of patients with PD (89)

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