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Radiation nephropathy can include azotemia (dangerously high levels of nitrogen waste products in the bloodstream), hypertension, and anemia, starting several months to years after treatment

Available at: (accessed August 25, 2025)

doi: 10.1074/jbc.M109.032888

Moreover, in animal models, ALC has been shown to attenuate the release of pro-inflammatory mediators (IL-1, TNF) from activated microglia, to modulate neuroinflammation and to reduce the concentration of oxidative stress markers, increasing the concentration of glutathione (GSH), a powerful mediator with antioxidant proprieties [27,28]

The opioid effects could only be detected by brain imaging