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Wan, Y., Zheng, Y

Antioxidants 11(7):1273 Aroniadou-Anderjaska V, Figueiredo TH, de Araujo Furtado M, Pidoplichko VI, Braga MF (2023) Mechanisms of organophosphate toxicity and the role of acetylcholinesterase inhibition

Interestingly, GH signaling leading to activation of lipolysis in adipose tissue and increased hepatic glucose production via both glycogenolysis and gluconeogenesis in the liver, is not affected by the absence of insulin crosstalk (reviewed in (72))

Additionally, RNA modification is a posttranscriptional event that can be regulated by ROS

Succinate accumulation inhibits -KGdependent TET and JMJD demethylases, promoting DNA and histone hypermethylation, whereas reduced -KG availability further constrains demethylation and limits enhancer plasticity