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In addition to the elevation of claudin-2, studies have revealed that ERK1/2 induced barrier disruption and increased TJ permeability through the ETS-like-1 protein (Elk)-1MLCK pathway (Table 1)

Even then, modest amounts (30-50 grams) often suffice

Capell-Hattam, I

Kan J, Cheng J, Hu C, et al

Every result was recorded to assess the 50% mechanical paw withdrawal threshold response (g)
