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10.1016/j.alcohol.2009.02.001 105.Mackillop J , Menges DP , McGeary JE , Lisman SA

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Increased ALOX5 expression elevated leukotriene B4 levels, promoted M1 macrophage polarization, and worsened cardiac injury, whereas ALOX5 knockout or pharmacological inhibition with zileuton reduced inflammation, preserved cardiac function, and improved survival (Xie et al., 2021)

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10.1097/00007632-199506000-00022 23 CaiF.HongX.TangX.LiuN