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The evolution of DDSs from passive carriers to intelligent, patient-centric platforms signifies promising progress in gout and hyperuricemia management, yet substantial challenges in clinical validation, scalability, and long-term safety persist, underscoring the need for sustained interdisciplinary efforts to fully realize their therapeutic potential

Updated May 20, 2021a

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Smoking and specific liver diseases Metabolic dysfunction-associated steatotic liver disease Among chronic liver disorders, MASLD is the most prevalent worldwide, with an estimated global prevalence of 2039%, depending on region, diagnostic method, and population studied [49,50,51]
