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Preclinical studies using metabolic assays such as euglycemic clamp techniques indicate that AOD 9604 does not impair insulin-mediated glucose uptake in adipose or peripheral tissues

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Bottom reading of the microplate provides better measurements since the distance between the cell layer and detector is reduced which minimizes unwanted effects from the cell culture medium

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Olsen RW, Li G-D (2011): GABA A receptors as molecular targets of general anesthetics: identification of binding sites provides clues to allosteric modulation