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This paradox may be partially explained by the cellular source: endothelial NOS (eNOS)-derived NO appears protective, while inducible NOS (iNOS) from macrophages tends to promote fibrosis [83]

It has also been hypothesized a role for melatonin suppression following sleep deprivation in the vascular impairment associated with sleep deprivation, given that melatonin inhibits oxidative stress and cytokine production by immune and vascular cells, and represses atherosclerotic lesion formation in vivo 209

Tietzes enzymatic recycling method to quantify glutathione The enzymatic recycling method described by Rahman et al

Savale L, Chaumais MC, Cottin V, et al
