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(96) found that EGCG blocked the transition of VSMCs from G1 to S phase by initiating the expression of p21/WAF1, which in turn inhibited NF-kappaB and AP-1-mediated VSMC proliferation

These changes can disrupt the integrity of sperm DNA, compromise membrane fluidity, and impair overall sperm functionality, further exacerbating infertility risks [9, 10]

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Front Cardiovasc Med (2023) 10:1187735

doi: 10.1016/j.nbd.2018.02.014
