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By disrupting the FOXO4-p53 interaction, it induces p53-mediated apoptosis, effectively clearing these damaged, senescent cells

Interventions that impede the aging process itself offer an alternative approach that may delay the onset of age-related chronic diseases and thus prolong healthy longevity

Johnsen SP, Hundborg HH, Sorensen HT, Orskov H, Tjonneland A, Overvad K, Jorgensen JO: Insulin-like growth factor (IGF) I, -II, and IGF binding protein-3 and risk of ischemic stroke

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Compared with the young control subjects, the elderly also had higher RBC concentrations of GSSG (0.11 0.04 compared with 0.15 0.05 mmol GSSG/L RBC