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FIGURE 2 HIF-1 is a DNA-binding protein and is composed of two different subunits, 120 kDa HIF-1 and 9194 kDa HIF-1 (Wang and Semenza, 1995)
Beloribi-Djefaflia, S., Vasseur, S
M., Jain V
Employing combined analyses of clinical patient samples and xenograft models, we further elucidate the pivotal role of Transcription Factor Binding To IGHM Enhancer 3 (TFE3), a master regulator of lysosomal biogenesis, in modulating malignant properties, particularly TMZ tolerance, by regulating peroxisome proliferator-activated receptor-gamma coactivator 1alpha (PGC1)-mediated mitochondrial activity
DOI: 10.3390/cells11030409 16
