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Another study that included 256 children showed that those with a deficiency of vitamin B12 had a higher than average body mass index

(3) Treatment and management Criteria The optimum dosage is 1000 g at intervals of eight weeks

Serious vitamin B12 deficiency may result in anemia, stomach problems, and nerve damage

In addition to its metabolic functions, biotin may also influence gene regulation: it can attach to specific lysine residues on histone proteins (a process known as histone biotinylation), thereby potentially affecting chromatin structure and gene expression

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