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Causality experiments further reinforce the central role of CCK in mediating anxiety vulnerability: selective knockdown of Cck within the mPFC of KI mice alleviated anxiety-like behaviors, whereas overexpression of Cck in WT mice was sufficient to induce heightened anxiety susceptibility

Gherasim et al., 2013

It does not cause cognitive blunting, weight changes, or withdrawal symptoms commonly associated with SSRIs and benzodiazepines

In rodents and humans, Delta sleep-inducing peptide (DSIP) influence in the secretion of adrenocorticotropic hormone (ACTH), luteinizing hormone (LH) and growth hormone (GH)

Bargou, R