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55 Although many variants affect the signalling ability of MC1R, the red hair colour variants D84E, R142H, R151C, R160W and D294Hwhich are associated with complete or partial loss of function of the MC1Rare especially associated with increased melanoma risk

Included were all patients who were older than 18 years but without confirmed heart disease, stroke, cancer, excessive alcohol consumption, autoimmune liver disease or other disorders potentially linked to fatty liver disease

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2f) providing strong evidence that Na + binding is allosterically coupled to carnitine binding