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An increasing body of research suggests that lipid peroxidation products exacerbate degenerative muscle changes by inducing oxidative stress, disrupting cell membrane structures, impairing mitochondrial function, and regulating cell death pathways

Instead, scientists foresee a future in which doctors offer a cocktail of medicines attuned to a patients biomarkers

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By disrupting the Keap1Nrf2 interaction, it promotes nuclear accumulation of Nrf2 and induces downstream cytoprotective genes such as HO-1 and NQO1, thereby attenuating reactive oxygen species accumulation and oxidative injury (255)