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plantarum activates toll-like receptors (TLRs) signaling, leading to the translocation of the pivotal structural protein Zonula occludens-1 (ZO-1) to the tight junction domain in intestinal models ( 5.3 SCFA production and anti-inflammatory effects Certain probiotic strains, particularly members of the Bifidobacterium and Lactobacillus genera, produce SCFAs, notably acetate, propionate, and butyrate, via the fermentation of dietary fibers ( The research by Peng et al

A better understanding of these physiological abnormalities could lead to the discovery of novel pathways for treatments of potentially many neurodevelopmental disorders and other neurological disorders involving abnormalities in these metabolic pathways

10.3389/fimmu.2022.823999 Front

Patients should be monitored for potential biphasic reactions following initial symptom resolution
