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Unlike other PDI family members that directly bind the substrates for their reductase or isomerase activities, the b domains of ERp57 have a high affinity to associate with calreticulin (CRT) and calnexin (CNX), which would help to recognize and recruit polypeptide segments of the glycoproteins

The resolution of lung injury by vitamin B 12 may be associated with its reduced glutathione-sparing effect to maintain the antioxidant status, as well as its role as a regulator of NFB levels affecting the expression of genes encoding pro-inflammatory cytokines

Dropout from interim methadone and subsequent comprehensive methadone maintenance American Journal of Drug and Alcohol Abuse, 35, 394-398 Gryczynski J, Schwartz RP, OGrady K, Jaffe JH (2009)

Plants also produce CO internally, mainly through heme oxygenase activity during heme turnover, and this is why CO is often discussed as a stress-linked gas signal (Mart-Guilln et al., 2022)
