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There is limited clinical data specifically on microdosing protocols

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10.3389/fpls.2016.01109 110 McGoldrickS.O'SullivanS

Given that portal delivery of insulin, which has the potential to completely restore IGF-I levels in type 1 diabetes (70, 71, 87), remains an experimental treatment, rhIGF-1 treatment to restore circulating IGF-I and suppress GH and decrease insulin needs appears to be the most feasible approach to take (88)
