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To achieve comparable effects, oral doses must be 30-50 times higher, creating cost and side effect challenges

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Sikiric et al., 2020b), the silver sulfadiazine cream (Mikus et al., 2001) or systemic corticosteroids (Sikiric et al., 2003), for possible wound healing therapy (i.e., incisional/excisional wound, deep burns, diabetic ulcer, and alkali burns) (Seiwerth et al., 1997