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Description
beta-Hydroxybutyrate inhibits myocardial fatty acid oxidation in vivo independent of changes in malonyl-CoA content

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Proces ten ma kluczowe znaczenie dla metabolizmu energetycznego komrek, zwaszcza komrek miniowych

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Our data suggest that inhibition of wildtype IDH1, depletion of KG through glutamine restriction, or inhibition of carnitine synthesis may act as a novel therapeutic approach in these cancers
