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Maintenance Therapy: Once the deficiency is fixed, smaller doses are needed

The major disadvantages of the aqueous liquid formulations are microbial contamination, chemical instability of the dissolved drug in aqueous conditions, presence of preservatives that may cause mucosal irritation, and short residence time in the nasal cavity due to mucociliary action [21]

PLoS ONE 12 , e0186459 (2017)

However, the population confinement blocked the generalizability of the present findings to other populations

For optimal study accuracy, complete your testing timeline within 21 to 30 days of mixing [verify with brand/source]