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Several potential neuroprotective targets have shown promise in preclinical studies, but failed to demonstrate efficacy in clinical trials, despite their effects on IOP and/or neuroprotection ( The term neuroprotection in the context of glaucoma refers to methods aimed at preventing damage and degeneration of RGCs and their axons, which are key features of the disease

doi: 10.1093/geront/gnv130 47 CuadradoA

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