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Structure, Catalytic Mechanism, and Evolution of the Glutathione Transferases
(PubMed) Beard J
Therefore, HIF-1 likely exerts a suppressive effect on ferroptosis in affected cells by upregulating antioxidant systems, exerting a protective role similar to its anti-apoptotic effects in osteoblasts
Brain GSH is decreased in AD and MCI in subgroup analysis
Upcoming studies may reveal additional therapeutic potential for edaravone, including its synergistic interactions with other compounds or its utility in addressing a wider spectrum of neurological diseases
