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445,446 A reduction of NAD + levels in cells is observed in many tissues with obesity, like the skeletal muscles, hypothalamus, liver and adipose tissue

Individuals who habitually eat certain raw fresh-water fish, raw shellfish, or ferns are at higher risk of thiamin deficiency because these foods contain thiaminase that normally is inactivated by heat in cooking (1, 6)

Symptoms usually vary depending on factors like personal chemistry, food in the system and the amount of alcohol consumed, among other factors

Following this period, the mice were randomly divided into five treatment groups ( n = 5 per group): PBS, Mn/TI@mHSA, P-Mn@mHSA, P-Mn/TI@mHSA-N and P-Mn/TI@mHSA group, with the doses equivalent for 4 mg kg 1 of Mn/TI@mHSA